80yr old female with Altered sensorium and CKD with late onset psychosis b/l osteoarthritis of knee

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80 yr old female was brought to the casualty with Chief complaints of 
   .Fever since 2 days
  . Altered sensorium since 2 days
   .loss of appetite since 2 days
Hopi: patient was apparently asymptomatic 2 days ago then she had fever high grade not associated with chills and rigor relieved with medication no diurnal variation altered sensorium since 2 days, irrelevant talk present.not able to identify the attenders,no h/o loss of consciousness, weakness in upper and lower limbs,no h/o chest pain palpitations sob,
loss of appetite and weight 
K/c/o HTN on tab atenolol
Kc/o ckd on conservative management
K/c/o AkI on CKD secondary to ruptured gluteal abscess 
With late onset psychosis

PERSONAL HISTORY-

Diet - Mixed 
Appetite - Decreased 
Bladder movements- Regular
Bowel movements- Regular
Sleep - Adequate
Allergy - No
Addictions - No
Family History:Not significant

General examination:
Patient is conscious 
No pallor,icterus,cyanosis,clubbing, lymphadenopathy 
PR:102/min
BP:100/60mmhg
RR:20/min
SPO2:94%


Systemic examination
CVS:S1 S2+. No murmurs
RS:BAE+
CNS
GCS:E4V4M6
Power:     Rt.  Lt
         UL.  cannot be elicited 
         LL.  cannot be elicited 

Tone. 
           UL.     N.    N  
            LL.      N.    N
Reflexes:
             B.    3+.     3+
             T.     3+.       3+
             S       2+.      2+
             K.      3+.      3+
             A.      2+.      2+
       Plantar flexion.  flexion 
P/A.     Soft,non tender

Investigations
Hb:8.4 gm/dl
TC:33200
PCV:26.0
RBC Count:2.65 millions
PLT COunt:2.73lacs
Urea:106
Creatinine:2.7
Uric acid:8.0
Ca:10.0
P:5.1
Na:139
K:4.1
Cl:101
CRP:positive
Blood lactate:5.9
CSF analysis
Sugar:61
Protein:9.5
Chloride:116
RBS:86
LFT :Total bilirubin :2.05
DB:0.42
Alkaline phosphate :162
ApTT test:35sec

                        Chest xray
                                ECG

 Provisional diagnosis :
Altered sensorium secondary to PYOGENIC MENINGITIS with AKI 



Treatment
 1.Ryles tube feed
 100ml water 2nd hrly
200ml milk 4th hrly
2.100ml NS
3.Inj .CEFTRIOXONE 1gm IV/BD
4.Inj.CLINDAMYCIN 600mg IV/BD
5.Inj.PAN 40mg IV/OD
6.Tab.NODOSIS RT/OD
7.Tab SHELCAL 500mg RT/OD
8.Tab.OROFER-XT RT/OD
9.Inj.DEXAMETHASONE 6mg IV/TID
10.Monitor vitals 2 nd hrly nd inform SOS
11.Strict input/output charting
 







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